(Stephen
Mackenzie, "The Etiology and Treatment of Acne Vulgaris,"
_British Medical Journal_, September 29, 1894. Laycock [_Nervous
Diseases of Women_, 1840, p. 23] pointed out that acne occurs
chiefly in those parts of the surface covered by sexual hair. A
lucid account of the origin of acne will be found in Woods
Hutchinson's _Studies in Human and Comparative Pathology_, pp.
179-184. G.J. Engelmann ["The Hystero-neuroses," _Gynaecological
Transactions_, 1887, pp. 124 et seq.] discusses various
pathological disorders of the skin as reflex disturbances
originating in the sexual sphere.)
The influence of menstruation in exacerbating acne has been
called in question, but it seems to be well established. Thus,
Bulkley ("Relation between Certain Diseases of the Skin and the
Menstrual Function," _Transactions of the Medical Society of New
York_, 1901, p. 328) found that, in 510 cases of acne in women,
145, or nearly one-third, were worse about the monthly period.
Sometimes it only appeared during menstruation. The exacerbation
occurred much more frequently just before than just after the
period.
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